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11 Signs and Symptoms of Vitamin A Deficiency

Vitamin A deficiency contributes to being a major cause on a worldwide scale for preventable blindness in children. 

If you, too, are anxious about diseases caused by deficiency of vitamin A, fret not! This particular article would act as a perfect guide and let you know all the vital facts about the deficiency of this vitamin.

Read through!

What is Vitamin A Deficiency?

In simple terms, the deficiency of the fat-soluble vitamin A refers to the inadequate presence of this vitamin in the body. The deficiency of this vitamin which is responsible for several bodily functions like a strong immune system, reproduction, good skin health and good vision, is found to be rarely present in developed countries but usually found in developing nations.

Vitamin A deficiency turns out to be a public health issue in over half of all the nations, and this especially includes the ones in South-East Asia and Africa.

How Common is Vitamin A Deficiency?

Vitamin A deficiency is relatively common, particularly in developing countries where diets may lack sufficient amounts of this essential nutrient. It is a significant public health issue, especially among young children and pregnant women, due to its critical role in vision, immune function, and overall health.

Efforts to address this deficiency often include supplementation programs, food fortification, and dietary diversity promotion to ensure adequate intake of vitamin A-rich foods.

What are the Signs & Symptoms of Vitamin A Deficiency?

This section would prove to be a comprehensive guide for an individual fretting as to what are the symptoms of vitamin A deficiency. The deficiency of this vitamin can be defined either subclinically or clinically, and a number of symptoms are associated with it.

Illustrated below are some of the vitamin A deficiency symptoms:

Sr.No. Symptom Description
1 Skin Dryness This vitamin is vital when it comes to the repair and formation of skin cells. It is also responsible for helping the body fight inflammation occurring as a result of some specific skin problems. Inadequate inputs of vitamin A might be the reason for the occurrence of eczema and other skin issues.

Eczema is a skin condition that can be blamed for the cause of dry, inflamed and itchy skin. Many clinical studies have shown that a prescription medicine having vitamin A activity named alitretinoin is effective when it comes to treating this skin condition.

In a particular 12 week study, it was noticed that individuals suffering from chronic eczema who were administered alitretinoin in 10 to 40 mg dosage per day experienced a reduction in their symptoms by up to 53%.

Regarding skin dryness, one must keep in mind that it can be caused due to various reasons, but a chronic deficiency of vitamin A might be a reason.
2 Dryness in Eyes Eye issues are known to be one of the most well-known vitamin A deficiency symptoms. In severe scenarios, inadequate inputs of this vitamin can result in total blindness or dying corneas characterised by marks known as Bitot’s spots.
The inability to produce tears or dry eyes forms one of the first symptoms of vitamin A deficiency. Young children belonging to Africa, India and Southeast Asia having a lack of vitamin A in their diet are at substantial risk for the development of dryness in the eyes. This condition can improve with vitamin A supplementation.
A specific study determined that high vitamin A doses caused a lowering of the prevalence of eye dryness among children and infants by 63% who received supplements for a period of 16 months.
3 Night Blindness Extreme deficiency of vitamin A can result in night blindness. Several observational studies reported that night blindness highly prevailed in developing countries. Owing to this problem’s extent, health professionals have worked towards improving the levels of vitamin A in individuals who are at risk of night blindness.
In a study, women having night blindness were administered vitamin A in the form of supplements or food, and both these forms of vitamin A led to an improvement in their condition. This was evident by the fact that the ability of the women in adapting to darkness increased by more than 50% over the six month treatment duration.
4 Infertility and Difficulty Conceiving Vitamin A is required for reproduction in the case of both women and men. It is also necessary for the proper development of babies.
The lack of vitamin A might be one of the reasons why a woman faces difficulty achieving pregnancy. Infertility in both women and men is one of the signs of vitamin A deficiency.
Other research suggested that due to the high levels of oxidative stress in the bodies of infertile men, they might have a higher requirement of antioxidants. For that case, vitamin A can again prove to be one of the nutrients providing a source of antioxidants in the body.
Miscarriages are also one of the effects of vitamin A deficiency. A study was conducted by analysing the levels of various nutrients in the blood of women who suffered recurrent miscarriages. Those women showed low vitamin A levels in their blood.
5 Stunted Growth Children not getting sufficient vitamin A might experience delayed growth.
A number of studies conducted on children from developing countries showed that vitamin A supplements could enhance growth. It was also found that other nutrients combined along with vitamin A as supplements showed a higher impact on growth.
6 Poor Healing of Wounds Low levels of vitamin A might be the reason for poor healing of wounds after a surgery or injury. The reason behind it is that this vitamin promotes the generation of a vital healthy skin component named collagen.
According to research results, both topical and oral vitamin A can help to strengthen the skin. Aged men who considered treating their wounds with topical vitamin A experienced a reduction of 50% in wound size compared to those who didn’t use them.
7 Acne and Breakouts As vitamin A helps fight inflammation and is also responsible for the promotion of skin development, it might help in the prevention or treating acne.
8 Chest and Throat Infections Frequent chest and throat infections might be a vitamin A deficiency disorder. Though the results from research are mixed, there has been evidence that vitamin A supplements might provide help with infections related to the respiratory tract.
9 Age-related Macular Degeneration (AMD) A major reason for significant loss of vision among older adults, AMD or age-related macular degeneration’s origin is generally unknown. But it is postulated that the cumulative effect of oxidative stress plays a role.
If that is the case, carotenoid containing supplements like beta-carotene, lutein, and zeaxanthin which have antioxidant functions, may prove useful for preventing this health condition. Particularly, zeaxanthin and lutein get accumulated in the retina, a tissue in the eye that gets damaged by AMD.
10 Cancer A number of studies have examined the link between cancer and vitamin A owing to the role which vitamin A plays in the regulation of cell growth and differentiation. However, there is a lack of clarity in the relationship between cancer risk and serum vitamin A levels or vitamin A supplementation.
11 Measles It is seen that measles is a major reason for mortality and morbidity in children from developing nations. Severe measles is known to be caused due to vitamin A deficiency.

While the above pointers answer what the symptoms of vitamin A deficiency are, individuals must also assess the reasons for vitamin A deficiency. Such knowledge can help when it comes to prevention.

Reasons that Cause Vitamin A Deficiency

The cause of vitamin A deficiency is getting an inadequate amount of vitamin A in the body.  Usually, dietary deficiency is the reason behind it, but there are chances that disorders interfering with the storage, transport or absorption of vitamin A might also cause a deficiency.

Pregnant women, infants, children and breastfeeding mothers are among those at a high risk of the deficiency of this vitamin.

In addition to these, a secondary deficiency might take place in individuals having underlying issues such as:

  • Cystic fibrosis
  • Cirrhosis
  • Chronic diarrhea
  • Celiac disease
  • Duodenal bypass
  • Bile duct obstruction
  • If you are wondering how vitamin A deficiency is diagnosed, an eye exam is used for that. The levels of vitamin A in the blood can be measured by a blood test.

What are the Diagnosis of Vitamin A Deficiency?

Diagnosis of the lack of vitamin A entails carrying out various essential methods for determining and confirming its presence in people.

Physical Examination

Through comprehensive physical examination, several signs can be identified which are related to vitamin A deficiency like skin and eyes dryness, night blindness, and delay in the wound healing process.

Dietary Assessment

This assists in identifying whether a patient is eating enough food containing vitamin A like liver, fish oils, dairy products and green leafy vegetables.

Serum Retinol Levels

Blood tests measure serum retinol levels to determine vitamin A status. Low levels of serum retinol are considered as deficient concentration which is defined as lower than 0.70 μmol/L (20 μg/dL).

Medical History Review

Checking medical history provides information on diseases that affect the absorption or utilisation of vitamin A such as malabsorption syndromes or liver diseases.

Ophthalmological Examination

The eyes are examined through an ophthalmological study including the detection of Bitot’s spots and other ocular manifestations caused by lack of vitamin A.

These diagnostic approaches enable healthcare providers to make the right diagnosis for vitamin A deficiency and initiate necessary interventions to manage it effectively.

How to Prevent & Overcome Vitamin A Deficiency?

Individuals looking for ways as to how to prevent vitamin A deficiency must note that eating dark green leafy vegetables, orange and yellow fruits like oranges and papayas, carrots, and yellow vegetables like squash and pumpkin are helpful in the prevention.

Milk and cereals are some other sources of food that are fortified with vitamin A. The carotenoids that give orange, red or yellow colour to vegetables and fruits, and get converted to vitamin A in the body are absorbed in the best manner from homogenized or cooked vegetables served with oil or fat.

For vitamin A deficiency treatment, both oral and injectable forms of vitamin A can be undertaken. In the oral form, vitamin A supplementation proves to be effective when it comes to reducing morbidity risk, especially from severe diarrhoea and lowering all-cause mortality and mortality arising out of measles.

Besides these, dietary diversification and food fortification also prove to be useful for overcoming vitamin A deficiency. The richest animal sources of vitamin A include the liver (cod liver oil and beef liver).

Individuals having deficiency of vitamin A are administered high vitamin A doses for several days, usually via the mouth. This is followed by lower doses until the conditions of skin and vision improvement. Repeated high doses should not be given to infants as such doses can prove to be toxic.

Best Food Sources to Overcome Vitamin A Deficiency

Make sure to include plenty of vitamin A-rich foods in your diet to prevent and treat deficiency. Below, you'll find a variety of top food sources, including fruits, vegetables, and other options, that are rich in this essential nutrient.

Fruits to Overcome Vitamin A Deficiency

Discover a selection of vitamin A-rich fruits highlighted in the table below, essential for overcoming and preventing deficiencies to support your health and well-being:

Sr.No. Fruit Vitamin A Content
1 Mango 112 mcg per whole mango
2 Cantaloupe 135 mcg per 1/2 cup
3 Dried Apricots 63 mcg per 10 halves
4 Red/Pink Grapefruit 143 mcg per medium-sized
5 Watermelon 28 mcg per 100 grams
6 Papaya 96 mcg per 100 grams
7 Guava 31 mcg per 100 grams
8 Goji Berries 26,822 IU per 1/2 cup dried
9 Tangerine 30 mcg per medium-sized
10 Nectarine 24 mcg per medium-sized
11 Passion Fruit 12 mcg per medium-sized

Vegetables to Overcome Vitamin A Deficiency

Take a look at a variety of vitamin A-rich vegetables in the table below, ranging from vibrant carrots to nutrient-packed spinach, essential for supporting your health and well-being.

Sr.No. Vegetable Vitamin A Content
1 Sweet Potato 1403 mcg per whole baked
2 Broccoli 60 mcg per 1/2 cup
3 Carrots 459 mcg per 1/2 cup
4 Spinach (Boiled) 573 mcg per 1/2 cup
5 Winter Squash (Cooked) 558 mcg per 100 grams
6 Kale (Cooked) 681 mcg per 100 grams
7 Turnip Greens (Cooked) 381 mcg per 100 grams
8 Parsley Rich source of vitamin A
9 Sweet Red Pepper (Raw) 117 mcg per 1/2 cup
10 Romaine Lettuce (Raw) 436 mcg per 100 grams
11 Collards (Cooked) 380 mcg per 100 grams
12 Swiss Chard (Raw) 306 mcg per 100 grams

Other Eatables to Overcome Vitamin A Deficiency

Here are some other foods, aside from fruits and vegetables, that are extremely rich sources of vitamin A:

Sr. No. Food Vitamin A Content
1 Beef Liver 5340 mcg per 100 grams
2 Cod Liver Oil 4080 mcg per tablespoon
3 Black-Eyed Peas 66 mcg per cup
4 Pumpkin Pie 488 mcg per serving
5 Tomato Juice 149 mcg per cup
6 Herring 36 mcg per 100 grams
7 Lamb Liver 7491 mcg per 100 grams
8 Liver Sausage 8300 mcg per serving
9 Salmon 149 mcg per 100 grams
10 Butter 684 mcg per 100 grams
11 Hard-Boiled Egg 74 mcg per large egg
12 King Mackerel 252 mcg per 100 grams
13 Bluefin Tuna 757 mcg per 100 grams
14 Goat Cheese 407 mcg per 100 grams
15 Trout 100 mcg per 100 grams
16 Cream Cheese 308 mcg per 100 grams
17 Caviar 271 mcg per 100 grams
18 Roquefort Cheese 294 mcg per 100 grams
19 Blue Cheese 198 mcg per 100 grams

How Much Vitamin A Do You Need Daily?

Different bodily functions like vision, immune health and cellular growth require different amounts of vitamin A per day. Age groups and stages of life determine RDA (Recommended Dietary Allowance) which lies between 300 to 1300 mcg RAE (Retinol Activity Equivalents) per day. This makes sure that individuals get enough amounts to cater for their specific nutritional requirements thereby upholding good health overall.

Age Recommended Amount
Birth to 6 months 400 mcg RAE
Infants 7–12 months 500 mcg RAE
Children 1–3 years 300 mcg RAE
Children 4–8 years 400 mcg RAE
Children 9–13 years 600 mcg RAE
Teen males 14–18 years 900 mcg RAE
Teen females 14–18 years 700 mcg RAE
Adult males 900 mcg RAE
Adult females 700 mcg RAE
Pregnant adults 770 mcg RAE
Breastfeeding adults 1,300 mcg RAE

Adjustments may be necessary based on factors such as food intake, and other health conditions.

Side Effects of Vitamin A Deficiency

If you don't address early signs of vitamin A deficiency, you may experience:

  • Night blindness 
  • Dry eyes and skin 
  • Increased susceptibility to infections, particularly respiratory infections 
  • Delayed growth in children 
  • Poor wound healing 
  • Reproductive complications, such as difficulty conceiving

These symptoms may not always be diagnosed as signs of vitamin A deficiency, but if left untreated, it can lead to severe outcomes. Taking early action through dietary changes, vitamin supplements, or medical treatment is crucial to prevent these serious health consequences associated with vitamin A deficiency.

Diseases Caused Due to Vitamin A Deficiency

Vitamin A deficiency may result in many severe ailments:

  • Night Blindness: It first displays difficulty seeing in dim light or at night which ends up causing total blindness.
  • Xerophthalmia: This type involves dry eyes which can cause blindness when not treated.
  • Infectious Diseases: Vitamin A insufficiency enhances disease vulnerability such as respiratory infections for instance measles and diarrhoea which sometimes cannot be avoided and become life-threatening, particularly among children.
  • Impaired Growth: The growth of affected children may be slow and their bone development may also take longer than normal.
  • Reproductive Issues: There are reproductive health challenges arising from vitamin A deficiency including high risks associated with maternal deaths and child deaths.
  • Immune System Impairment: There could be a decline in the strength of our immune systems meaning more frequent and worse illnesses.

Early identification and treatment through dietary adjustments, supplementation, or medical intervention are crucial to prevent these health complications associated with vitamin A deficiency.

Treatments for Vitamin A Deficiency

Addressing vitamin A deficiency involves a combination of dietary adjustments and medical interventions to restore adequate levels of this essential nutrient. Below are the common treatments:

Treatment Method Description
Oral Vitamin A Supplements Prescribed supplements in the form of capsules or liquid to replenish vitamin A stores in the body.
Dietary Adjustments Increasing intake of vitamin A-rich foods such as liver, sweet potatoes, carrots, spinach, and other leafy greens.
Fortified Foods Consuming foods fortified with vitamin A, such as fortified milk, breakfast cereals, and margarine.
Cod Liver Oil A natural source of vitamin A, cod liver oil can be consumed to boost vitamin A levels.
Monitoring and Evaluation Regular medical supervision and periodic blood tests to monitor vitamin A levels and adjust treatment as necessary.

How Long Does it Take to Fix Vitamin A Deficiency?

Vitamins, on a biological scale, get absorbed within a few hours and show immediate metabolic effects. Having mentioned that, there exist several factors which affect their efficacy, prevent the body from fully absorbing them and hence helps determine how long it takes to correct vitamin A deficiency. These include:

  • Levels of Deficiency: If someone is highly deficient in a specific mineral or vitamin, it might take up a long time for its rectification. Alternatively, there might be a necessity for a high dosage to ensure a faster recovery.
  • Supplement Type: Vitamins administered in the capsule form would, in most cases, have a slower effect than in liquid form. This is due to the fact that the body needs to break down a capsule and extract the vitamins present inside.
  • Fat vs Water-soluble Vitamins: Fat-soluble vitamins like vitamin A need fat to be absorbed. This can only take place by taking them along with food or mixing the nutrients with a fat present in the liquid or capsule. Vitamins that are fat-soluble in nature are stored in the body and hence might not require regular or high doses like the ones that are water-soluble in nature.
  • Nutrient Pairing: There are a number of minerals and vitamins which are interrelated in the way they work. They get better absorbed if they are paired with each other. 
  • Habits and Lifestyle: Some particular lifestyle habits and factors like smoking and drinking alcohol might cause malabsorption, and a higher intake might be necessary for maintaining equilibrium.
  • Health Issues: Certain health problems can result in malabsorption like some people cannot absorb some vitamins due to gut diseases like coeliac or inflammatory bowel disease.

Who is at Risk of Suffering from Vitamin A Deficiency?

Some people are more at risk of developing vitamin A deficiency due to factors that affect how the body produces, absorbs, or uses this nutrient. Identifying these risk factors is important for detecting deficiency early and managing it effectively.

  • Young Children: Infants and young children are at risk because of inadequate intake of vitamin A-rich foods in their diet and high demands for nutrition during growth.
  • Pregnant and Breastfeeding Women: Pregnant women and lactating mothers may lack the required increased vitamin A intake.
  • Individuals with Poor Diets: Lack of a variety of fruits, vegetables and animal products in one’s meals can lead to an insufficient supply of vitamin A.
  • People with Malabsorption Issues: Conditions like Crohn’s disease, cystic fibrosis or certain surgical operations make it hard for the body to absorb fat-soluble vitamins like vitamin A, via food.
  • Those with Liver Diseases: some liver conditions might damage the ability to convert vitamin A affecting its presence in a person.
  • Alcoholics: It interferes with the absorption and storage of this vitamin in the liver when alcohol is taken excessively over a long period.
  • Individuals with Certain Health Conditions: Conditions affecting bile production or pancreatic function may also lead to reduced absorption of vitamin A.
  • Vegetarians and Vegans: Those who do not consume animal products need to ensure adequate intake of provitamin A carotenoids found in fruits and vegetables.
  • People in Low-Income Countries: Deficiency is common where vitamin A-rich diets are scarce or expensive.

After going through this article regarding vitamin A deficiency, you are now aware of which disease is caused by deficiency of vitamin A and all other related facts. Every individual must be aware of these facts as it would help them take care of themselves and their close ones.

Frequently Asked Questions

What are the risks of consuming excessive amounts of vitamin A?

 Consuming too much vitamin A is referred to as toxicity. It can cause adverse health effects, including liver abnormalities, birth defects, disorders of the central nervous system, lowering of bone mineral density, which in turn results in a greater risk of osteoporosis.

What is the prognosis for a deficiency due to vitamin A?

 If treatment is done in the initial stages of vitamin A deficiency, the prognosis is good. Otherwise, it might prove fatal in the later stages. In addition, certain conditions such as keratomalacia, keratopathy and rupture of the cornea are irreversible in nature.

What is meant by hypervitaminosis?

Vitamin A toxicity is also referred to as hypervitaminosis, which defines the condition when there is an excessive amount of vitamin A in the body. This condition can either be a chronic or acute one.

A chronic condition is when there is vitamin A build-up over a long time period. An acute condition generally occurs when there is an excessive vitamin intake within a short time span.

What are the symptoms of low vitamin A?

Symptoms of low vitamin A (deficiency) include night blindness, dry eyes, increased susceptibility to infections, dry skin, poor wound healing, and in severe cases, complete blindness.

What are the side effects of too little vitamin A?

Insufficient vitamin A can lead to impaired vision, compromised immune function, and delayed growth in children. It may also affect skin health, increasing susceptibility to infections.

How to increase vitamin A?

You can increase your vitamin A intake by consuming foods rich in retinol (animal sources like liver, eggs, and dairy) or provitamin A carotenoids (plant sources like carrots, sweet potatoes, and spinach) and taking vitamin A supplements as recommended by a healthcare provider.

What happens if your vitamin A is low?

Low vitamin A can lead to a range of health issues including vision problems, weakened immune response, and slower wound healing. It is essential for maintaining healthy skin, eyes, and overall immune function.

What foods are high in vitamin A?

Foods high in vitamin A include liver, fish liver oils (like cod liver oil), dairy products, eggs, and brightly coloured fruits and vegetables such as carrots, sweet potatoes, spinach, kale, and cantaloupe.

What happens if I have too much vitamin A?

Excessive intake of vitamin A, especially from supplements, can lead to toxicity symptoms such as nausea, headache, dizziness, blurred vision, and in severe cases, liver damage or bone abnormalities.

How much vitamin A do you need?

The Recommended Dietary Allowance (RDA) for vitamin A varies by age and gender. For adults, it ranges from 700 to 900 micrograms of Retinol Activity Equivalents (RAE) per day, depending on age and gender.

How common is vitamin A deficiency?

Vitamin A deficiency is a significant public health issue in many developing countries, particularly affecting young children, pregnant women, and populations with limited access to diverse diets.

What are the three symptoms of severe vitamin A deficiency?

Severe vitamin A deficiency can manifest as night blindness, dry skin (xerosis cutis), and in extreme cases, corneal ulcers leading to irreversible blindness.

Does a lack of vitamin A result in hair loss?

Hair loss is not typically a direct symptom of vitamin A deficiency. However, vitamin A is essential for maintaining healthy skin, which indirectly affects hair health.

When using vitamin A, what should you avoid?

When using vitamin A supplements or medications (like isotretinoin for acne), it's advisable to avoid excessive sun exposure as it can increase the risk of sunburn due to increased skin sensitivity.

Is vitamin A a source of energy?

Vitamin A itself does not provide energy like carbohydrates or fats. Instead, it plays crucial roles in various physiological processes such as vision, immune function, and cell growth.

What effects does vitamin A have on your skin?

Vitamin A promotes healthy skin by supporting cell production and turnover, which helps maintain skin integrity and prevent conditions like acne and dryness.

Who is most at risk for vitamin A deficiency?

Groups at higher risk include young children with limited diets, pregnant or breastfeeding women, individuals with malabsorption disorders (e.g., Crohn's disease), and those living in regions with food insecurity.

What age group needs more vitamin A?

Children and pregnant or breastfeeding women have increased vitamin A requirements due to growth, development, and fetal/maternal health needs.

What drink is high in vitamin A?

No specific drink is exceptionally high in vitamin A, but beverages made from fortified milk (such as fortified dairy milk) or vegetable juices containing carrots can contribute to vitamin A intake.

Which Indian food is rich in vitamin A?

Indian foods rich in vitamin A include vegetables like carrots, spinach, sweet potatoes, and leafy greens such as fenugreek leaves (methi) and amaranth leaves (chaulai).