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What is Packed Cell Volume or PCV Blood Test?

In blood, PCV stands for Packed Cell Volume. The percentage of blood made up of cells is measured by the packed cell volume (PCV). The percentage or fraction of cells in the blood is used to express the value.

Almost all the blood cells in the human body are red blood cells. PCV blood test or haematocrit test is one of the tests that measure the proportion of RBC in a blood sample.

Continue reading this article to know more about the PCV test.

What Is PCV in a Blood Test?

PCV in a blood test measures the proportion of red blood cells, which is made up of cells. The count of PCV rises due to the increase in the count of red blood cells or when the total volume reduces, as in the case of dehydration. In case the PCV becomes less than normal, it indicates anaemia. This test is also known as the haematocrit test. Generally, the PCV test is a part of a full blood count test. Human blood is a mixture of cells and plasma

Why is a PCV Test Necessary?

A PCV, or Packed Cell Volume Test, is a general blood screening done to determine dehydration (low body fluids or blood volume), polycythemia (high levels of red blood cells), or anaemia (low levels of red blood cells) in certain patients. 

This test is used to diagnose or evaluate anaemia (reduction of red blood cells), polycythaemia (increase in red blood cells), or dehydration, which may be referred to as relative polycythaemia.

When Should I Get the PCV Test?

For several reasons, a physician may suggest a packed cell volume (PCV) test, also called a haematocrit test: 

  • Normal Blood Tests: As a component of a standard physical examination or complete blood count (CBC).
  • Signs: If you have any symptoms, such as headaches, dizziness, exhaustion, pale skin, shortness of breath, anaemia, polycythaemia, or dehydration, consult your doctor.
  • Pregnancy: To keep an eye on anaemia levels.
  • Treatment: To track how you respond to anaemia or other medical condition therapies or evaluate how well treatments work.

A PCV test determines the percentage of red blood cells in your blood. A PCV level below normal may be a sign of dehydration, polycythaemia, anaemia, or other illnesses.

What is the Procedure for the PCV Test?

The PCV test is performed by taking a little sample of blood from the patient's vein and putting it into a special tube. The tube is then centrifuged, which causes the blood cells to settle at the bottom corner of the test tube and the plasma to rise to the top.

How Should You Prepare for the PCV Test?

To prepare for the PCV test, individuals do not need to take any special preparation before a PCV test. However, if someone is anxious, it is best to consult the doctor. Moreover, if a person has any medical condition or is using any medication, he/she must convey the information to the doctor. Individuals do not have to fast before taking a PCV test.

How is PCV Measured in Blood Tests?

A tiny amount of blood is drawn from the patient's vein for the PCV test and placed into a specialised tube. The tube is then centrifuged, causing the plasma to rise to the top and the blood cells to settle at the bottom corner of the test tube. 

A PCV test typically ranges from 35.5% to 48.6%, with women's range being 35.5% to 44.9% and men's range being 38.3% to 48.6%. If a physician suspects dehydration, polycythaemia (too many red blood cells), or anaemia (too few red blood cells), they may order a PCV test.

How to Read Results of PCV in a Blood Test?

A lower count of PCV means a loss in RBC count due to several reasons, such as cell destruction, low bone marrow production and blood loss. An increased PCV means there is an increase in the production of red blood cells and dehydration.

On taking a look at the tube of centrifuge, one can figure out the white blood cells count as well. It is a buffy count that typically lies between the red cell and plasma layer.

Normal Range of PCV in a Blood Test

The results of PCV tests are given as percentages. If the PCV blood test results indicate a level of 50%, red blood cells fill 50 millilitres by volume in 100 millilitres of blood. Any increase or reduction in this value could be a sign of several illnesses and issues, some of which might be chronic.

The PCV test normal range varies depending on gender, age, and other factors.

S. No. Normal Range Gender
1 38-52% Males
2 34-58% Females

Having PCV levels below or above the recommended levels may mean different things for different people depending on their symptoms and testing requirements.

S. No. Range Status
1 < 35.5 Low
2 35.5 - 48.6 Normal
3 > 48.6 High

Symptoms of High PCV

The primary causes of high PCV include pulmonary or lung diseases, heart diseases, kidney cancer, and genetic disorders. 

Go through the following table to see the symptoms of high PCV. Individuals having high PCV levels experience the following symptoms:

Symptoms Description
Flushed Skin Increased red blood cells make the skin look reddened or flushed due to the high blood flow and vascular congestion.
Dizziness The thicker blood can reduce the efficiency of blood flow to the brain, leading to dizziness or lightheadedness.
Vision Problems High PCV can lead to changes in blood flow in the eyes, potentially causing blurred vision or visual disturbances.
Headaches Increased blood viscosity results in high blood pressure and reduced oxygen delivery to the brain, causing headaches.
Enlarged Spleen The spleen may enlarge (splenomegaly) in filtering and managing the increased red blood cells, leading to pain in the upper left abdomen.

These symptoms indicate the body's struggle to manage the high volume of red blood cells and can be associated with underlying conditions that require medical evaluation and management.

What If PCV in Blood is High?

The most common treatment for High PCV is frequent blood withdrawals. Certain medications, such as antihistamines and selective serotonin reuptake inhibitors, ease the symptoms of high PCV. Several drugs, such as Hydroxyurea, Interferon alfa-2b, Rutolitinib, and Busulfan, treat high PCV. 

Furthermore, there are various preventive measures to avoid high PCV. These measures include:

  • Exercising regularly to reduce the odds of blood clots
  • Cut down on tobacco intake
  • Avoid living in environments with low-oxygen
  • Avoid bathing in hot water, heated whirlpools, and hot tubs

What are the Causes of High PCV?

High-packed cell volume, or hematocrit, shows a high percentage of red blood cells in the blood. The causes of high PCV include the following:

Causes Description
Dehydration Plasma volume reduction from fluid loss or inadequate fluid intake may concentrate red blood cells and raise PCV.
Polycythemia Vera This bone marrow disorder causes excessive production of red blood cells.
Chronic Lung Diseases Lung disorders, like chronic obstructive pulmonary disease, increase red blood cells as a response to low oxygen levels.
Heart Disease Conditions of the heart may occur, leading to secondary erythrocytosis.
Kidney Disease Most kidney diseases are caused by excessive erythropoietin, which increases the hormone level that stimulates the formation of RBCs.

High PCV can also be an acclimatisation response to residing at high altitudes, whereby the body produces more red blood cells to facilitate better transportation of oxygen. If you think that you might have a high PCV, contact your healthcare provider to gain appropriate evaluation and management.

Symptoms of Low PCV

Medical experts associate low PCV with several medical conditions, such as chronic bleeding, bone marrow disorder, cancer, kidney failure, thalassemia, skin cell anaemia, and autoimmune diseases.

When an individual has a low PCV level, they have the following symptoms

Symptoms Description
Pale Complexion The skin's noticeable paleness can occur due to reduced blood flow, anaemia, or other underlying health conditions.
Weakness A lack of physical strength or energy can make everyday tasks or activities difficult. Various factors, including illness or nutritional deficiencies, can cause this.
Fatigue A state of extreme tiredness or exhaustion that is not relieved by rest. It can result from overwork, lack of sleep, or medical conditions.
Low Energy A general feeling of reduced vitality or endurance, where an individual feels less able to engage in regular activities or maintain usual activity levels.
Breathing Trouble Difficulty breathing, which may include shortness of breath, wheezing, or a feeling of breathlessness, can be a sign of respiratory or cardiovascular issues.
Irregular Breathing An abnormal breathing pattern, such as rapid, slow, or erratic breaths. It can be associated with various conditions, including anxiety, respiratory disorders, or heart problems.
Cold Feet or Hands A sensation of coldness in the hands and legs, even during summer, might indicate poor circulation, anaemia, or other circulatory issues.

What If PCV in Blood is Low?

Low PCV is treated with iron, vitamin B-12, and folic acid supplements. Blood transfusion, bone transplant, oxygen therapy, and pain relief medications are also used.

Moreover, the following preventive measure helps to avoid low PCV in a blood test –

  • Follow a healthy diet
  • Stay hydrated and drink enough water
  • Exercise regularly
  • Wash your hands frequently
  • Take proper care of your teeth
  • Consult a doctor if you experience any symptom

Lifestyle and demographic factors affect an individual's haematocrit level, which further influences the results of a PCV test. Pregnant women may experience reduced PCV levels, and strength training can also reduce them.

What are the Causes of Low PCV?

Low PCV (packed cell volume), also known as low hematocrit, indicates a lower proportion of red blood cells in the blood. The causes of low PCV can include:

Causes Description
Anaemia Various forms include iron-deficiency anaemia, vitamin B12 or folate deficiency, and chronic disease.
Chronic Blood Loss From conditions like gastrointestinal bleeding, heavy menstruation, or trauma.
Bone Marrow Disorders Conditions like aplastic anaemia, leukaemia, or other myelodysplastic syndromes affect red blood cell production.
Hemolysis Increased destruction of red blood cells due to conditions such as hemolytic anaemia or autoimmune disorders.
Kidney Disease Chronic kidney disease can reduce erythropoietin production, essential for red blood cell production.
Nutritional Deficiencies Iron, vitamin B12, or folate deficiency can lead to decreased red blood cell production.
Chronic Inflammation or Infection Chronic diseases or infections that affect red blood cell production or lifespan.

A thorough evaluation by a healthcare provider is necessary to determine the specific cause and appropriate treatment.

Other Factors that Influence PCV Levels

Besides the primary causes of low PCV, several other factors can influence PCV (packed cell volume) levels:

  • Hydration Status: Dehydration can increase PCV, while overhydration or fluid retention can dilute red blood cells, leading to a lower PCV.
  • Pregnancy: Increased blood volume during pregnancy can result in a relative decrease in PCV.
  • Altitude: Living at high altitudes can increase PCV as the body produces more red blood cells to compensate for lower oxygen levels.
  • Physical Activity: Extreme physical exertion can temporarily alter PCV levels.
  • Medications: Certain drugs, such as diuretics or chemotherapy agents, can affect PCV levels.
  • Temperature: Severe cold or heat can impact red blood cell concentration and volume.

Changes in PCV levels can often be a combination of these factors and underlying health conditions.

Low Packed Cell Volume (PCV) can be treated in various ways, from taking supplements to considering more intense therapies. These measures depend heavily on maintaining and restoring ideal blood health. If you're searching for a reliable provider for PCV testing, get skilled professionals to come to your home on your schedule for optimal convenience.

FAQs about PCV in Blood Tests

What is the normal PCV range?

The normal PCV range for men is 38.3% to 48.6%. Similarly, for women, the normal range is 35.5% to 44.9%.

What is a haematocrit test?

The haematocrit test or PCV test measures the proportion of RBC in blood. It is a common blood test used to evaluate the overall health and detect conditions such as anaemia, dehydration, and other blood disorders.

What will happen if PCV is low?

A low PCV (Packed Cell Volume) indicates that a smaller proportion of your blood comprises red blood cells. Reduced oxygen delivery to tissues can lead to symptoms like fatigue and weakness, which may signal anaemia or other health issues.

What happens when PCV is high?

A high PCV (Packed Cell Volume) means a larger proportion of your blood comprises red blood cells. This can indicate dehydration, polycythemia (an overproduction of red blood cells), or lung and heart diseases.

What does a PCV of 34 mean?

A PCV (Packed Cell Volume) of 34% means that 34% of the blood's volume is composed of red blood cells. This value can help indicate your overall red blood cell count and how well your body is oxygenating your tissues.

Is 32 PCV normal for a woman?

No, the normal range for females is 35.5 to 44.9%. For pregnant females, the normal PCV is 33-38%. The normal range of PCV generally depends on the person taking the test.

What to take when PCV is low?

Treatment for low PCV anaemia usually involves taking iron supplements and changing the diet. If the cause of iron deficiency is blood loss, finding the source of the bleeding and stopping it is needed.

What are the signs and symptoms of low PCV?

Common signs and symptoms include fatigue, weakness, dizziness, pale skin, and shortness of breath. In severe cases, it can lead to irregular heartbeats and chest pain. It's important to consult a healthcare provider for accurate diagnosis and treatment.

How can I increase my PCV?

Do the following to increase your PCV:

  • Eat iron-rich foods
  • Eat foods rich in vitamin B12
  • Eat foods rich in folic acid
  • Take supplements
  • Stay hydrated
  • Exercise regularly
  • Get enough sleep

Which is the best fruit for blood?

Citrus fruits like oranges, lemons, and grapefruit contain antioxidants, including flavonoids. Consuming flavonoid-rich citrus fruits may help reduce blood pressure and stiffness in your arteries while improving blood flow and nitric oxide production.

Is 30 PCV normal for pregnant women?

No, the normal PCV range in pregnant females is 33-38%. This lower-than-average PCV range is due to high blood fluid levels during pregnancy. In some cases, a PCV value of 30% (mild anaemia) is also observed.

What is the cause of high PCV levels in a blood test?

The most common cause of increased PCV is dehydration; with adequate fluid intake, the PCV returns to normal. However, it may reflect polycythaemia, with too many red cells.

Is the PCV test painful?

No, the PCV test is a simple blood test that is usually painless, although some people may experience slight discomfort or bruising at the site where the blood was drawn.

How often should I get tested?

Your health and medical history depend on how often you should get a packed cell volume (PCV) test. A healthcare provider can advise you on how often you should get tested based on your circumstances.

Does PCV change with blood loss?

Yes, PCV changes with blood loss. Blood loss reduces red blood cell count. Consequently, PCV decreases with blood loss.

What are the types of PCVs?

There are two types of PCV, they are:

  • Hematocrit (Hct)
  • Mean Corpuscular Volume (MCV)

What are the risks of a Packed Cell Volume (Hematocrit) test?

The PCV test is generally safe. Potential risks include minor bruising, discomfort at the needle site, and a small chance of bleeding or infection. These risks are minimal and typically managed easily.