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What is Chikungunya Virus Infection: Meaning, Transmission and Prevention

The Chikungunya virus has captured worldwide attention because of its quick spread and debilitating symptoms. Infected Aedes mosquitoes are the primary vector for the Chikungunya virus (CHIKV), which causes the disease chikungunya. 

The potential for Chikungunya outbreaks and their effects on daily life make it a pressing public health concern that warrants thorough attention and inquiry.

What is Chikungunya?

Chikungunya is a viral disease spread among individuals by infected mosquitos. It is caused by the chikungunya virus and is characterised by high fever and severe joint pain.

The term "chikungunya" is derived from a word in the Kimakonde language that translates to "that which bends up," referring to the deformed appearance of those suffering from joint discomfort.

How is Chikungunya Transmitted?

Chikungunya virus transmission happens via numerous methods, the most common of which being mosquito bites:

  • Mosquito Vector

The virus is predominantly spread by the bite of infected Aedes mosquitos, specifically Aedes aegypti and Aedes albopictus. When these mosquitos feed on an infected person during an epidemic, they become virus carriers.

  • Transmission Through Blood 

Chikungunya virus can be spread by infected blood, which is uncommon. Cases have been reported among laboratory workers working with infected blood and healthcare personnel drawing blood from infected patients.

  • In-utero Transmission

Transmission from mother to foetus has been observed in rare cases, primarily during the second trimester.

  • Intrapartum Transmission

Transmission can occur during childbirth if the mother is infected during delivery.

What are the Symptoms of Chikungunya?

Chikungunya symptoms usually develop in 4-8 days after being bitten by an infected mosquito.

  • High Fever

The sickness occurs abruptly, with a high temperature as a major symptom.

  • Joint Pain

Chikungunya is characterised by significant joint pain, which is often devastating. This discomfort might last for days, weeks, months, or even years. Joint swelling is common as well.

  • Muscle Pain

Muscle discomfort occurs when muscles hurt and become uncomfortable.

  • Weariness

Severe weariness, headaches and nausea accompany the sickness.

How is Chikungunya Diagnosed?

Chikungunya diagnosis entails numerous approaches and considerations:

  • Clinical Evaluation 

If you recently travelled to a region where the virus is known to be transmitted and have a high fever and joint discomfort, your doctor may suspect Chikungunya and order diagnostic tests.

  • Serological Tests

Serological studies, such as enzyme-linked immunosorbent assays (ELISA), establish the presence of anti-chikungunya IgM and IgG antibodies. IgM antibodies often peak three to five weeks after the onset of symptoms and last for two to three months. IgG antibodies begin about two weeks after the onset of symptoms and can remain for years.

  • Direct Viral Detection

The virus can be identified directly in the blood during the early stages of infection. Serological and virological approaches are used to test samples collected within the first week of sickness.

  • Differential Diagnosis

Blood testing can also look for viruses that are similar to Chikungunya, such as dengue and Zika.

Typically, test results are available 4 to 14 days after the laboratory receives the specimen.

What is the Treatment for Chikungunya?

Because there is no specific vaccine or antiviral treatment for Chikungunya, treatment focuses on symptom alleviation and prevention measures. Here are some recommendations for Chikungunya treatment:

  • Rest and hydration

Adequate rest and staying hydrated are critical for recovery and symptom control.

  • Medication for Pain and Fever

Over-the-counter pain medicines such as acetaminophen or paracetamol can help lower temperature and relieve discomfort.

  • Avoid NSAIDs

Aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) should be avoided until dengue has been ruled out, as these medications can increase the risk of bleeding.

How to Prevent Chikungunya?

Chikungunya prevention mostly entails mosquito control and personal protection measures. 

Here are some important tips for avoiding Chikungunya:

  • Precautions for Travel:
    • Use Protective Items: Insect repellents and mosquito nets should be used.
    • Practice Isolation: When feasible, stay in air-conditioned or well-screened hotels.
  • Personal Safety:
    • Wear Safety Clothing: Wear long-sleeved shirts, long pants, socks, and closed-toe shoes when going outside to minimise exposed skin.
    • Apply Insect Repellent: Apply insect repellents certified by the EPA to exposed skin and clothing. Apply again as recommended.
    • Breeding Hours: Stay indoors during peak mosquito activity hours, which are usually dawn and night.
    • Mosquito Nets: Mosquito nets should be used, especially for newborns and young children.
  • Protection from Mosquitos:
    • Remove Mosquito Breeding Spots for Mosquito Control: Mosquitoes breed in stagnant water, so reduce standing water around your home. Empty all containers, such as flower pots, tyres, and buckets regularly.
    • Larvicides: To kill mosquito larvae, treat water storage containers with larvicides.
    • Maintain Shields: Ensure your windows and doors have screens to keep mosquitos out of your home.

What are the Risk Factors of Chikungunya?

Chikungunya can affect anyone, but certain circumstances can make infection and consequences more likely. The following are the risk factors for Chikungunya:

Location

Living in or going to areas with active Chikungunya transmission raises the risk of exposure to infected mosquitoes. Chikungunya is more common in tropical and subtropical regions.

Mosquito Exposure

Spending time outside without sufficient protection, especially during peak mosquito activity hours (dawn and dusk), increases the risk of mosquito bites and Chikungunya transmission.

Weak Immunity

People not previously afflicted with Chikungunya or immunised against it are more susceptible to the infection.

Age Groups

While Chikungunya can affect people of all ages, elderly people and infants are more likely to develop severe symptoms and problems.

Medical Conditions

Individuals with underlying medical issues, such as diabetes, heart disease, or weakened immune systems, may have more severe forms of Chikungunya and its consequences.

Pregnancy

Chikungunya-infected pregnant women are at risk of problems, and the virus can be passed on to the foetus during pregnancy or childbirth.

Mosquito-borne Disease Co-Infections

People with other mosquito-borne diseases, such as dengue or Zika, may have more severe symptoms and complications.

Occupational Exposure

Certain vocations, such as outdoor labourers or those involved in mosquito control, may be at a higher risk of being bitten by an infected mosquito.

Chikungunya, a viral disease spread by Aedes mosquitos, is a major public health concern due to its rapid spread and debilitating symptoms. While it is rarely fatal, it can cause long-term joint difficulties. Early detection is critical for effective symptom management. Preventive strategies include mosquito control and personal protection, particularly in endemic areas.

FAQs about Chikungunya

Is the Chikungunya virus treatable?

There is no specific antiviral treatment for chikungunya; nevertheless, several therapeutic alternatives are being researched. Rest, drinks, analgesics and antipyretics may be used to treat symptoms. Nonsteroidal anti-inflammatory medications (NSAIDs) can be used to treat fever and pain.

What age does chikungunya occur?

It is more common in people aged 40 to 50. The most common symptoms reported among the overall symptomatic cases are fever, headache, and joint discomfort.

Is chikungunya harmful to the lungs?

During CHIKV infection, a strong inflammatory response may result in the clinical pathogenesis observed in ill individuals, impacting numerous organ systems such as the brain, heart, lungs, kidneys, skin, and joints.